Notice of Funding Opportunity PS23-003: Exploring Preferences for Long-Acting Antiretroviral Therapies (LA-ART) in a Community-Based Sample of Priority Populations Living with HIV Who are Disproportionately Affected

This website is designed to:

• Support the application process for health departments applying for Notice of Funding Opportunity (NOFO) PS23-003, and
• Provide a forum for the dissemination of important information to potential applicants.

This Notice of Funding Opportunity announcement is available at www.grants.gov. The view the entire announcement go to www.grants.gov and click on the “Search Grants” tab. Then enter  “RFA-PS23-003” into the “Basic Search Criteria-Opportunity Announcement. To learn more about the CDC application process, visit grants.gov How to Apply for Grants webpage.

Executive Summary

Creating equitable access to HIV treatment and care for people with HIV (PWH) includes successful uptake of new and emerging treatments, such as long-acting antiretroviral therapies (LA-ART), which offer advantages such as convenience and reduced stigma compared to daily oral treatment. Inequities in HIV include the disproportionate rate of HIV among cis-gender Black women with HIV (CgBWH).  CgBWH account for nearly 60% of new HIV infections in US women, despite making up less than 15% of the female population. Due to a host of social determinants of health (SDOH) like racism, poverty, stigma, unequal access to health care, and housing and educational inequities, CgBWH bear the highest burden of HIV infection among US women. Given this disproportionate rate of infection and related SDOH, the focus population of this NOFO is CgBWH. This NOFO supports the Ending the HIV Epidemic in the U.S. (EHE) initiative “Treat” Pillar. Specifically, the EHE plan lists CgBWH as a priority population to focus on for prevention, care and treatment interventions and resources for the greatest impact in reaching the National HIV/AIDS Strategy (NHAS) goals. This Notice of Funding Opportunity (NOFO) will support formative research on acceptance and perceived barriers and facilitators of using current and future long-acting antiretroviral therapies among cis-gender Black women with HIV (CgBWH).

Purpose

The purpose of this NOFO is to use an exploratory qualitative approach as a unique source of information about LA-ART from the perspectives and experiences of CgBWH, including barriers and facilitators to uptake and use, and individual and systemic supports needed to facilitate delivery of this therapy. Use of a qualitative research design is expected to yield details and nuances of decision-making and circumstances related to uptake of LA-ART that may not be possible to gather through quantitative data collection methods alone. Interviews and focus groups should include information on LA-ART delivery methods that are currently approved or in clinical trials, such as administration, ART class, frequency of dosing, safety, efficacy, and adverse drug reactions. The findings of this research are expected to inform strategies to strengthen uptake and adherence to ART and reduce existing disparities in HIV viral suppression among CgBWH.

Application is due on 03/17/2023 and can be downloaded from https://www.grants.gov/web/grants/view-opportunity.html?oppId=343368. Please direct questions to Jocelyn Patterson Mosley, MPH, MA, Scientific/Research Contact JPatterson@cdc.gov, 404-639-6437.