HIV Surveillance Supplemental Report — Volume 28, Number 3

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Estimated HIV Incidence and Prevalence in the United States, 2017–2021

Key Findings

Estimated HIV Infections in the United States Over Time*

Estimated HIV infections decreased 12% overall from 2017 to 2021.
Estimated HIV Infections in the United States Over Time

Estimates for years 2020 and 2021 should be interpreted with caution. See Technical Notes for more information.
*Among people aged 13 and older.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Differences in Estimated HIV Infections by Assigned Sex at Birth*†

Men accounted for a majority (81%) of estimated HIV infections in 2021.
Differences in Estimated HIV Infections by Assigned Sex at Birth

*Among people aged 13 and older.
Based on assigned sex at birth. Data for gender are not provided because the estimates for transgender people and people of additional gender identity are too small to report.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Differences in Estimated HIV Infections by Transmission Category*

Gay, bisexual, and other men who reported male-to-male sexual contact accounted for the highest percentage of estimated HIV infections in 2021.
Differences in Estimated HIV Infections by Transmission Category

*Among people aged 13 and older.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Differences in Estimated HIV Infections by Race/Ethnicity*†

Racial and ethnic differences in estimated HIV infections persist. Racism, HIV stigma, discrimination, homophobia, poverty, and other barriers to health care continue to drive these disparities.
Differences in Estimated HIV Infections by Race/Ethnicity

*Among people aged 13 and older.
Data for Native Hawaiian and other Pacific Islander are not included because estimates are too small to report.
Hispanic/Latino people can be of any race.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Differences in Estimated HIV Infections by Age

People aged 13 to 34 accounted for more than half (58%) of estimated HIV infections in 2021.
Differences in Estimated HIV Infections by Age

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Estimated HIV Infections by Region*

The South accounted for more than half (52%) of estimated HIV infections in 2021.
Estimated HIV Infections by Region

*Among people aged 13 and older.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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Knowledge of HIV Status in the United States*

In 2021, an estimated 1.2 million people had HIV.
For every 100 people with HIV, 87 knew their HIV status.

*Among people aged 13 and older.

Source: CDC. Estimated HIV incidence and prevalence in the United States 2017–2021. HIV Surveillance Supplemental Report 2023;28(3).

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The HIV Surveillance Supplemental Report is not copyrighted and may be used and reproduced without permission. Citation of the source is, however, appreciated.

Suggested Citation

Centers for Disease Control and Prevention. Estimated HIV incidence and prevalence in the United States, 2017–2021. HIV Surveillance Supplemental Report, 2023; 28 (No.3). http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html. Published May 2023. Accessed [date].

Confidential Information, Referrals, and Educational Material on HIV

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Acknowledgments

Publication of this report would not have been possible without the contributions of the state and territorial health departments and the HIV surveillance programs that provided surveillance data to CDC.

This report was prepared by the following staff and contractors of the Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, CDC: Anna Satcher Johnson, Ruiguang Song, Anna D. Baker, Zanetta Gant, Baohua Wu, Sue Reynolds, Cindy Lyles, Alex Viguerie, Paul Farnham, Angela L. Hernandez Juliet Morales, Michael Friend (editing and desktop publishing), and Azfar Siddiqi (science review).

The following are acknowledged for their contributions to the report (including graphics) and report website: Prevention Communications Branch (Content and Infrastructure Team); the Division of Communication Services, Mikaelyn Benson, Deirdre Launt, Meredith Newlove, Cesar Rivera (Design Team).